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What will cause skin's barrier function to change?  

Our skin’s barrier function fluctuates due to several reasons.

Temperature
Barrier function is weaker in winter than summer.

Parts of our body
Barrier function of facial skin is lower than that of body skin.

Gender
Barrier function in women is found to be lower than in men.

Skin’s barrier function is also weaker when there is stress and skin needs more time to recover than in its normal condition.